Anti-Cancer Powder Erlotinib hydrochloride CAS 183319-69-9

Payment Type: L/C,T/T,Paypal
Incoterm: FOB,CIF
Min. Order: 10 Gram
Delivery Time: 3 Days

Basic Info

Model No.: CAS 183319-69-9

Additional Info

Packaging: 10g 100g 1kg

Productivity: 50 kg/month

Brand: cy

Transportation: Ocean,Land,Air

Place of Origin: China

Supply Ability: 50kg

Certificate: ISO 9001, GMP

Port: QINGDAO,SHANGHAI

Product Description

Name Erlotinib hydrochloride
Other Name ERLOTINIB HCL
CAS No. 183319-69-9
EINECS N/A
MF C22H24ClN3O4
MW 429.9
MP 223-225°C
Storage temp. -20°C Freezer
Purity 99% min
Usage Erlotinib hydrochloride is a kind of small molecule epidermal growth factor receptor tyrosine kinase reversible inhibitor. It is mainly used for the second-line or third-line treatment of locally advanced or metastatic non-small cell lung cancer and for the treatment of pancreatic cancer.

Erlotinib hydrochloride is the hydrochloride salt of a quinazoline derivative with antineoplastic properties. Competing with adenosine triphosphate, erlotinib reversibly binds to the intracellular catalytic domain of epidermal growth factor receptor (EGFR) tyrosine kinase, thereby reversibly inhibiting EGFR phosphorylation and blocking the signal transduction events and tumorigenic effects associated with EGFR activation.


Properties:
Appearance & Physical State: White or off-white powder
Melting Point: 223-225ºC
Boiling Point: 553.6ºC at 760 mmHg
Flash Point: 288.6ºC
Vapor Pressure: 4.52E-12mmHg at 25°C

COA

tems

Specifications

Results

Appearance

White off-white crystalline powder

White off-white crystalline powder

 

 

Identification

Infared Absorption

Complies

The retention time of the major peak  

 in the chromatogram of the 

Assay prepration corresponds to that in

 the  chromatogram of the standard preparation,

 as obtained in the assay

complies

Specific rotation

Between -28.6°and -35.0°, measured at   20°

-32.8°

Water

not more than 0.5%

0.12%

residue on ignition

not more than 0.2%

0.11%

Heavy metals

not more than 0.001%

complies

Assay

102.0% ocalculated   with  reference to the Anhydrous Basis

99.8%



Contact Information

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Contact Person: Jerry

Phone:86-0531-18560179988

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