AP26113 Brigatinib analog ALK-IN-1 CAS 1197958-12-5

Payment Type: L/C,T/T,Paypal
Incoterm: FOB,CIF
Min. Order: 10 Gram
Delivery Time: 3 Days

Basic Info

Model No.: CAS 1197958-12-5

Additional Info

Packaging: 10g 100g 1kg

Productivity: 100 kg/month

Brand: cy

Transportation: Ocean,Land,Air

Place of Origin: China

Supply Ability: 50kg

Certificate: ISO 9001, GMP

Port: QINGDAO,SHANGHAI

Product Description

Prodcut name

AP26113

Synonyms

5-chloro-2-N-[4-[4-(dimethylamino)piperidin-1-yl]-2-methoxyphenyl]-4-N-(2-dimethylphosphorylphenyl)pyrimidine-2,4-diamine;(2-((5-Chloro-2-((4-(4-(dimethylamino)piperidin-1-yl)-2-methoxyphenyl)amino)pyrimidin-4-yl)ami;AP26113;AP26113/AP-26113;5-chloro-N2-(4-(4-(diMethylaMino)piperidin-1-yl)-2-Methoxy-5-Methylphenyl)-N4-(2-(diMethylphosphoryl)phenyl)pyriMidine-2,4-diaMine;5-Chloro-N2-[4-[4-(dimethylamino)-1-piperidinyl]-2-methoxyphenyl]-N4-[2-(dimethylphosphinyl)phenyl]-2,4-pyrimidinediamine;(2-((5-chloro-2-((4-(4-(dimethylamino)piperidin-1-yl)-2-methoxyphenyl)amino)pyrimidin-4-yl)amino)phenyl)dimethylphosphine oxide;AP26113-analog (ALK-IN-1)

MOQ

10G

CAS No.

1197958-12-5

Appearance

white powder

Molecular Formula

C27H36ClN6O4P

Molecular Weight

575.039301

Assay

99%

Application

Pharma grade or research purpose

Packing

As per your request

Storage

Preserve in tight,light-resistant containers in a cool place

Remarks

NA

Custom synthesis

 Available

Supply Ability

50kg/month

Brigatinib-analog is an orally active, potent and selective anaplastic lymphoma kinase (ALK) and the epidermal growth factor receptor (EGFR) inhibitor. Brigatinib-analog is structurally related to Brigatinib (AP-26113). Brigatinib-analog binds to and inhibits ALK kinase and ALK fusion proteins as well as EGFR and mutant forms. This leads to the inhibition of ALK kinase and EGFR kinase, disrupts their signaling pathways and eventually inhibits tumor cell growth in susceptible tumor cells.

Contact Information

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Shandong Chenyi Environmental Protection Technology Co.,Ltd

Contact Person: Jerry

Phone:86-0531-18560179988

Fax:

Address: No.215 Beiyuan Main street,tianqiao District,Jinan,Shandong

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