Payment Type: | L/C,T/T,Paypal |
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Incoterm: | FOB,CFR,CIF,FCA,CPT |
Min. Order: | 25 Kilogram |
Delivery Time: | 5 Days |
Basic Info
Model No.: cas 14639-25-9
Additional Info
Packaging: 25kg
Productivity: 10000
Brand: cy
Transportation: Ocean,Land,Air
Place of Origin: China
Supply Ability: 10
Certificate: ISO 9001, GMP
Port: QINGDAO,SHANGHAI
Product Description
Product Name: |
Chromium picolinate |
Synonyms: |
CrPic;Picolinic acid chromium;CHROMIUM PICOLINATE NF;Picolinic Acid Chromium(III) Salt Chromium(III) Pyridine-2-carboxylate Pyridine-2-carboxylic Acid Chromium(III) Salt;chromium(iii)trispicolinate;chromium2-pyridinecarboxylate;tris(2-pyridinecarboxylato-n(1),o(2))-chromiu;tris(picolinato)-chromiu |
CAS: |
14639-25-9 |
MF: |
C18H12CrN3O6 |
MW: |
418.3 |
EINECS: |
1592732-453-0 |
Product Categories: |
Food additives;Classes of Metal Compounds;Cr (Chromium) Compounds;Transition Metal Compounds |
Mol File: |
14639-25-9.mol |
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Chromium picolinate Chemical Properties |
storage temp. |
room temp |
Merck |
14,2236 |
CAS DataBase Reference |
14639-25-9(CAS DataBase Reference) |
EPA Substance Registry System |
Chromium, tris(2-pyridinecarboxylato-. kappa.N1,.kappa.O2)-(14639-25-9) |
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Safety Information |
Hazard Codes |
Xi |
Risk Statements |
20/21/22-36/37/38 |
Safety Statements |
22-36/37/39-36-26 |
RTECS |
US5647790 |
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MSDS Information |
Provider |
Language |
Picolinic acid chromium(III) salt |
English |
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Chromium picolinate Usage And Synthesis |
Product Features |
Chromium
picolinate appears as fine purple crystalline powder with good fluidity. It
is chemically stable at room temperature and is slightly soluble in water but
insoluble in ethanol, wherein the chromium is in the trivalent form. The
whole molecule structure is electrically neutral and has hydrophobic
properties. Therefore, it is possible to perform the trans-membrane
absorption on the intact structure with the molecular structure being similar
to the GTF part. In 1977, Toepfer thought that GTF is the biologically active
form of chromium with its structure being the complex formed between
nicotinic acid chromium and aspartic acid, glutamic acid, glycine and
cysteine. The GTF-like structure of chromium picolinate class determines its
own excellent absorption rate and can more effectively play its biological
function. It is reported that the absorption rate of formulation of ordinary
chromium was about 0.5% while the absorption rate of chromium is 2%-5%
(Anderson, 1996). |
Chromium |
Chromium is one
of 12 kinds of essential trace metal element. In natural environment,
chromium is presented in various valence states from Cr to Cr6 + with Cr, Cr2
+, Cr3 +, Cr6 + being the most widely existed. Cr3 + is an essential trace
element in the human body and is the form of the entire chromium inside human
body. It is the component comprising glucose tolerance factor with the
insulin-like effects. Therefore, it can promote glucose utilization of cells,
promote the oxidative phosphorylation of glucose, promote glycogen promote
synthesis as well as improve the stability of insulin, thereby reducing blood
sugar level. Its physiological role has been increasingly drawn the attention
of researchers. Studies have shown that: chromium is closely related to
glucose metabolism, lipid metabolism, protein metabolism and nucleic acid
metabolism. It has also found that many kinds of animals have strong chromium
tolerance with the capability of tolerating 3000 mg/kg of chromium oxide and
1000 mg/kg of chromium chloride. Chromium picolinate, as organic chromium
preparation, has their safety being drawn a growing concern. In livestock
production, chromium picolinate can significant promotion effect on
alleviating environmental stress, increasing lean meat rate and increasing
the endurance and is thus widely used. However, for their usage amount,
although some countries have ratified chromium picolinate to be added to
poultry diets, currently there has not yet of officially released minimum
requirement and maximum tolerated dose data of animals. Studies have reported
that normal physiological plasma concentration of chromium is 0.1-2.1μg/ml
(Cerulli et al., 1998), the physiological concentrations of chromium in human
liver was 5.4-470ηg / g liver wet weight (-0.1-9μM) (Versieck, 1985).
Excessive addition (much higher than physiological dose) may produce toxicity
DNA and cytotoxicity. |
Precautions |
At present,
according the research of domestic and international research institutions
and Nutrition Institute, long-term intake of chromium ≥1000ug/day can easily
lead to poisoning. The maximal allowable consumption amount for health food
is 250ug/day. |
Uses |
It can be used as
a medicine and health products as well as food additives. |
Chemical Properties |
Dark violet crystal |
CONTACT US
Shandong Chenyi Environmental Protection Technology Co.,Ltd
Contact Person: Jerry
Phone:86-0531-18560179988
Fax:
Address: No.215 Beiyuan Main street,tianqiao District,Jinan,Shandong