Payment Type: | L/C,T/T,Paypal |
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Incoterm: | FOB,CIF |
Min. Order: | 1 Gram |
Delivery Time: | 3 Days |
Basic Info
Model No.: CAS 231277-92-2
Certification: GMP
Additional Info
Packaging: 10g 100g 1kg
Productivity: 10000
Brand: chenyi
Transportation: Ocean,Land,Air
Place of Origin: China
Supply Ability: 10
Certificate: Enterprise standard
HS Code: 2934999090
Port: QINGDAO,JINAN
Product Description
Lapatinib is a synthetic, orally-active quinazoline with potential antineoplastic activity. Lapatinib reversibly blocks phosphorylation of the epidermal growth factor receptor (EGFR), ErbB2, and the Erk-1 and-2 and AKT kinases; it also inhibits cyclin D protein levels in human tumor cell lines and xenografts. EGFR and ErbB2 have been implicated in the growth of various tumor types. Check for active clinical trials or closed clinical trials using this agent.
Properties:
Appearance & Physical State: Powder
Density: 1.381 g/cm3
Boiling Point: 750.7ºC at 760 mmHg
Flash Point: 407.8ºC
Refractive Index: 1.645
Vapor Pressure: 0mmHg at 25°C
Fuction
Lapatinib is used in combination with capecitabine for the treatment of erbb-2 overexpression, and has previously been treated
with anthracycline, taxol, and trastuzumab (herceptin) for advanced or metastatic breast cancer.Lapatinib, an anti-cancer drug
developed and manufactured by glaxosmithkline, was approved by the us food and drug administration on March 13, 2007.The currently
approved indication is the combination with Capecitabine for advanced or metastatic breast cancer, which must be treated with
other first-line drugs and fails.Its U.S. product name is Tykerb, while in Europe it will be Tyverb once approved by the European
governing body.Lapatinib is unique in that patients who have been treated with other chemotherapy drugs do not develop
cross-resistance to it and can effectively slow the progression of breast cancer.There are many other clinical trials underway to
study the effects of lapatinib on other cancers.
CONTACT US
Shandong Chenyi Environmental Protection Technology Co.,Ltd
Contact Person: Jerry
Phone:86-0531-18560179988
Fax:
Address: No.215 Beiyuan Main street,tianqiao District,Jinan,Shandong