High quality Cediranib /Recentin AZD-2171 CAS 288383-20-0

Payment Type: L/C,T/T,Paypal
Incoterm: FOB,CIF
Min. Order: 1 Gram
Delivery Time: 5 Days

Basic Info

Model No.: CAS 288383-20-0

Additional Info

Packaging: 1G

Productivity: 1 kg/month

Brand: cy

Transportation: Ocean,Land,Air

Place of Origin: China

Supply Ability: 1 kg

Certificate: ISO 9001, gmp

Port: QINGDAO,SHANGHAI

Product Description

Cediranib (AZD-2171) Introduction

Cedinib is a pan-VEGF receptor tyrosine kinase inhibitor. It mainly inhibits VEGFR-1, VEGFR-2, VEGFR-3 and PDGFR. Cetanib inhibits three vascular endothelial growth factor (VEGF) receptors, acts on blood vessels and lymphatic vessels, exerts anti-angiogenic effects, and inhibits tumor growth and spread.

 [Product Name]: Cediranib (AZD-2171) powder

 [Apperance]:white powder

 [Specification]:99%

 [Test Method]:HPLC


Cediranib (AZD2171) is a potent inhibitor of vascular endothelial growth factor (VEGF) receptor tyrosine kinases.



Cediranib (AZD2171) inhibited VEGF-stimulated proliferation and KDR phosphorylation with IC50 of 0.4 and 0.5 nM, respectively.


Cediranib, also known as AZD-2171, is a potent and selective VEGF inhibitor with antineoplastic activities. Competing with adenosine triphosphate, cediranib binds to and inhibits all three vascular endothelial growth factor receptor (VEGF-1,-2,-3) tyrosine kinases, thereby blocking VEGF-signaling, angiogenesis, and tumor cell growth.


Properties:
Density: 1.285
Boiling Point: 626.557ºC at 760 mmHg
Flash Point: 332.73ºC
Refractive Index: 1.642
Vapor Pressure: 0mmHg at 25°C

cediranib mechanism of action

Contact Information

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