high quality NN-dicyclohexylcarbodiimide (dcc) CAS 538-75-0

Payment Type: L/C,T/T,Paypal
Incoterm: FOB,CIF
Min. Order: 25 Kilogram
Delivery Time: 3 Days

Basic Info

Model No.: CAS 538-75-0

Additional Info

Packaging: 25KG Drum

Productivity: 300 T/year

Brand: chenyi

Transportation: Ocean,Land,Air

Place of Origin: China

Supply Ability: 100 T

Certificate: ISO 9001,GMP

Port: QINGDAO,SHANGHAI

Product Description


Dicyclohexylcarbodiimide


CAS No.  538-75-0

Appearance   White crystal or yellowish liquid


Assay  ≥99%


Capacity  100mt/year




More information



Molecular Formula: C13H22N2

Molecular Weight: 206.33

CAS Registry Number: 538-75-0

EINECS: 208-704-1

Melting point: 33-35 ºC

Boiling point: 122-124 ºC (6 torr)

Flash point: 87 ºC

USAGE

    It is used in the synthesis of amikacin and amino acids. It is a good dehydrating agent at low temperature. It is also used in the synthesis of acid, anhydride, aldehyde and ketone.Dehydrating agents for glutathione account for 90% of total consumption in Japan.When the product is used as a dehydrating and shrinking mixture, it can be formed by a short time reaction at room temperature. After the reaction, the product is dicyclohexyl urea.Because the solubility of the product in organic solvent is very small, the reaction product is easy to separate.At the same time, because the product is difficult to dissolve in water, the reaction can continue even in an aqueous solution.This product is also used for the synthesis of peptides and nucleic acids. It is easy to synthesize peptides with free carboxyl groups and free amino groups at room temperature with high yield.Used for the production of blood pressure increasing hormone, cyclic adenosine phosphate.



    It is mainly used for condensation of amino acids in synthetic polypeptide.In Fmoc- solid phase synthesis, the carboxyl group of an amino acid forms an amide bond with the amino group of another amino acid.To make the carboxyl group more susceptible to attack by the nucleophile, negatively charged oxygen atoms need to be activated into a better leaving group first, and DCC plays this role.The carboxyl oxygen atom on the amino acid ACTS as a nucleophile to attack the carbon atom in the middle of the DCC molecule so that the DCC can combine with the carboxyl group to form an ester structure, making the nucleophile attack of the amino group easy.



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