Payment Type: | L/C,T/T,Paypal |
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Incoterm: | FOB,CIF |
Min. Order: | 25 Kilogram |
Delivery Time: | 3 Days |
Basic Info
Model No.: CAS 40064-34-4
Colour: Colorless To Pale Yellow Liquid
CAS: 872-85-5
Purity: 98%
Additional Info
Packaging: 25kg
Productivity: 30 T/year
Brand: chenyi
Transportation: Ocean,Land,Air
Place of Origin: China
Supply Ability: 10T
Certificate: ISO 9001,GMP
Port: QINGDAO,SHANGHAI
Product Description
4-Pyridine carboxaldehyde chemical property
4,4-Piperidinediol hydrochloride
Name 4-Piperidone Hydrochloride Monohydrate
Synonym More Synonyms
Chemical & Physical Properties
Boiling Point 175.1ºC at 760 mmHg
Melting Point 97-99 °C
Molecular Formula C5H12ClNO2
Molecular Weight 153.607
Flash Point 84.6ºC
Exact Mass 153.055649
PSA 52.49000
LogP 0.18150
Storage condition Store at 0-5°C
APPLITION:
4,4-Piperidinediol hydrochloride can be used as a pharmaceutical intermediate for the synthesis of other compounds with certain activity. Examples of the application of 4,4-piperidinediol hydrochloride are as follows:
4,4-piperidinediol hydrochloride can be used to synthesize P-gp inhibitors. The P-glycoprotein has a molecular weight of 170 kD and contains two highly consistent -NH2 nitrogen ends and a -COOH carbon end. There are 6 transmembrane helices and 1 nucleotide binding site at each end. Overexpression of P-glycoprotein is usually present in patients with tumor recurrence after chemotherapy drug treatment and in cells layered by chemotherapeutic drugs. The classical method of interfering with P-glycoprotein function is to use small molecules as P-glycoprotein inhibitors, often referred to as multidrug resistance modulators, which inhibit the function of the P-glycoprotein efflux pump and ultimately lead to tumors. Effective aggregation of intracellular drugs.
COA
CONTACT US
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