Top quality Dovitinib Tki258 CAS 915769-50-5 with best price

Payment Type: L/C,T/T,Paypal
Incoterm: FOB,CFR,CIF,FCA,CPT
Min. Order: 10 Gram
Delivery Time: 2 Days

Basic Info

Model No.: CAS 915769-50-5

Additional Info

Packaging: 10g 100g 1kg

Productivity: 10000

Brand: cy

Transportation: Ocean,Land,Air

Place of Origin: China

Supply Ability: 10

Certificate: ISO 9001, GMP

Port: QINGDAO,SHANGHAI

Product Description

Dovitinib


CAS NO. 405169-16-6

USAGE

Dovitinib, also known as TKI-258 or CHIR-258, is an orally bioavailable FGFR3 inhibitor, which strongly binds to fibroblast growth factor receptor 3 (FGFR3) and inhibits its phosphorylation, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell death. In addition, this agent may inhibit other members of the RTK superfamily, including the vascular endothelial growth factor receptor; fibroblast growth factor receptor 1; platelet-derived growth factor receptor type 3; FMS-like tyrosine kinase 3; stem cell factor receptor (c-KIT); and colony-stimulating factor receptor 1; this may result in an additional reduction in cellular proliferation and angiogenesis, and the induction of tumor cell apoptosis.

COA


Item

Standard

Test Results

Identification

A.H-NMR:Comply with the structure

Complies

B.LC-MS:Comply with the structure

Complies

C.The IR spectrum of sample should be identical with that of reference standard.

Complies

D.HPLC-ESI-MS

The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay.

Complies

Loss on drying

≤2.0%

0.19%

Heavy metals

≤10 ppm

<10ppm

Water

≤1.0%

0.1%

Sulphated ash

≤0.5% determined on 1.0 g.

0.009%

Residue on ignition

≤0.1%

0.03%

Related Substances

Unspecified impurities: for each impurity

≤0.10%

<0.10%

Total Impurity

≤0.5%

0.18%

Purity

≥99.0%

99.7%

Assay

99.0%~101.0% (anhydrous substance).

99.8%

Storage

Preserve in well-closed, light-resistant and airtight containers.

Complies

 



Contact Information

CONTACT US

Shandong Chenyi Environmental Protection Technology Co.,Ltd

Contact Person: Jerry

Phone:86-0531-18560179988

Fax:

Address: No.215 Beiyuan Main street,tianqiao District,Jinan,Shandong

Full name Contact Phone Content
点击刷新验证码