White solid Ropivacaine HCl CAS 98717-15-8

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Min. Order: 1 Kilogram
Delivery Time: 5 Days

Basic Info

Model No.: CAS 98717-15-8

Additional Info

Packaging: 1 kg

Transportation: Ocean,Land,Air


Product Description

English alias: Ropivacaine hcl; N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride (1:1)
CAS: 132112-35-7

Properties: white to off-white crystal or crystalline powder

At 25°C ropivacaine HCl has a solubility of 53.8 mg/mL in water, a distribution ratio between n-octanol and phosphate buffer at pH 7.4 of 14:1 and a pKa of 8.07 in 0.1 M KCl solution. The pKa of ropivacaine is approximately the same as bupivacaine (8.1) and is similar to that of mepivacaine (7.7). However, ropivacaine has an intermediate degree of lipid solubility compared to bupivacaine and mepivacaine.

It`s pharmacological characteristics are low cardiotoxicity, and the separation of sensory block and motor block is obvious, and it has peripheral vasoconstriction. Therefore, the drug is especially suitable for postoperative analgesia and obstetric anesthesia.
Ropivacaine has the following advantages over traditional local anesthetics:
1, the effect of the effect - ropivacaine for a longer time than other long-acting local anesthetics, subcutaneous infiltration anesthesia time is 2 to 3 times longer than the same concentration of bupivacaine.
2, unique efficacy - ropivacaine sensory - motor block separation is much greater than bupivacaine, and higher clearance, making it more suitable for analgesia.
3, strong controllability - ropivacaine anesthesia effect in a dose-dependent manner, that is, the degree of sensation and motor block produced by ropivacaine is predictable and controllable.
4, low toxic side effects - ropivacaine does not have the general long-acting local anesthetic cardiotoxicity of the major defects, the product rarely occurs cardiotoxicity, and the fetus is well tolerated by this product.

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